Genetic Mutation in Black Americans Boosts Risk of Transthyretin Amyloidosis
The V142I variant of the TTR gene, common among Black Americans, increases risks of cardiac amyloidosis, heart failure, and early mortality.
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Specialty: Heart & Vascular
The V142I variant of the TTR gene, common among Black Americans, increases risks of cardiac amyloidosis, heart failure, and early mortality.
Read More...Researchers at Brigham and Women’s Hospital developed a novel aortic stenosis polygenic risk score (PRS) that incorporates more than five million genetic variants. They verified it was associated with aortic stenosis in two independent, very large populations.
Read More...By reviewing data from a long-term prospective study of U.S. women, researchers at Brigham and Women’s Hospital identified 12 biomarkers associated with premature CHD. They discuss the potential implications of biomarker screening and therapeutic strategies.
Read More...Conventional CPR, which combines rescue breathing with chest compressions, has been the primary treatment for cardiac arrest for nearly 60 years. Survival, however, remains frustratingly low. Brigham and Women’s Hospital is part of a collaborative effort to explore a promising new alternative: extracorporeal…
Read More...Direct oral anticoagulants (DOACs) are preferred to vitamin K antagonists for stroke prevention in atrial fibrillation, acute treatment and extended-duration secondary prevention of venous thromboembolism in most patients. However, DOACs may be less efficacious or safe compared to standard of care in other conditions.
Read More...Behnood Bikdeli, MD, MS, at Brigham and Women’s Hospital, David Jiménez, MD, PhD, at Hospital Ramón y Cajal in Madrid, and colleagues recently conducted the first study to compare the prognostic relevance of cTnI with hs-cTnI in patients with pulmonary embolism (PE).
Read More...Using a very large U.S. prospective cohort from the Million Veteran Program, Brigham and Women’s Hospital researchers report that a higher intake of red meat, either processed or unprocessed, was associated with a higher risk of cardiovascular disease.
Read More...On May 16 – 19, 2024, faculty from the Heart & Vascular Center at Brigham and Women’s Hospital will join the international electrophysiology community and present their latest research at the Heart Rhythm 2024 annual meeting.
Read More...Researchers from the Brigham, the Broad Institute, and Stanford Medicine combined multiple sequencing and experimental techniques to map the relationship between known coronary artery disease (CAD) variants and the biological pathways they impact.
Read More...Brigham researchers are challenging the trend of deprescribing statins in people over 75 years of age. Ariela Orkaby, MD, MPH, led a trio of studies of statin use in older adults with chronic kidney disease, older adults with and without frailty, and adults with heart failure with preserved ejection fraction.
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