Meta-analysis: Effect of EPA vs. EPA+DHA Omega-3 Fatty Acids on Cardiovascular Outcomes

Deepak L. Bhatt, MD, MPH, of the Interventional Cardiovascular Program at Brigham, and colleagues, recently performed a systematic review and meta-analysis and report that prescription EPA treatment, and not EPA+DHA supplementation, is associated with reductions in cardiovascular mortality and related outcomes.

Read More...

Cardiac Risk Substantially Lower with Enzalutamide Than Abiraterone

Using the world’s largest pharmacovigilance database, Eugene B. Cone, MD, Quoc-Dien Trinh, MD, and colleagues determined the risk of cardiac adverse events is increased substantially with abiraterone and not at all with enzalutamide.

Read More...

Myocardial Blood Flow Reserve Is an Early Marker of Myocardial Decompensation in Patients with Aortic Stenosis

Echocardiography image doppler of aortic stenosis

Marcelo F. DiCarli, MD, of the Cardiovascular Imaging Program at the Brigham, and Wunan Zhou, MD, MPH, at the NIH, and colleagues report that impaired myocardial blood flow reserve is an early marker of adverse myocardial characteristics and can identify patients who might benefit from aortic valve replacement.

Read More...

Morbidity and Mortality from Mitral Valve Surgery After TEER: First CUTTING-EDGE Data

Team of cardiologists perform transcatheter closure treatment

Tsuyoshi Kaneko, MD, of the Heart & Vascular Center at Brigham, served as the first author of the initial analysis of CUTTING-EDGE data. Two key findings are that 93% of patients required MV replacement and one-year cumulative mortality for the entire cohort was 24%.

Read More...

Striatin Deficiency Is Associated With Enhanced Thrombosis

3D Rendering of an Aldosterone Molecular Model

Jose R. Romero, PhD, and colleagues have now used a prevous model of patients with rs2540923 to show that striatin serves a protective role in the hemostatic system, which may be reduced in humans with striatin risk alleles.

Read More...

Biological Sex Modifies Aldosterone Secretion at a Cellular Level

3D Rendering of the Adrenal Gland

Gordon H. Williams, MD, senior physician in the Division of Endocrinology, Diabetes and Hypertension at the Brigham, Shadi K. Gholami, PhD, research fellow, and colleagues have expanded on their earlier work to determine if biological sex affects the production of aldosterone levels.

Read More...

Scientific Statement: COVID-19 and Heart Failure

In September 2021, the Heart Failure Society of America published a scientific statement that discusses clinical care for patients with HF during the COVID-19 pandemic. Ankeet S. Bhatt, MD, MBA, of the Division of Cardiovascular Medicine at the Brigham, was a co-chair of the writing committee and first author.

Read More...

Synopsis: ACC/AHA Guidance on Management of Secondary Mitral Regurgitation

Sameer Hirji, MD, MPH, and Tsuyoshi Kaneko, MD, of the Division of Cardiac Surgery at the Brigham, and colleagues summarize the revised recommendations about caring for patients with secondary mitral regurgitation now that transcatheter edge-to-edge mitral repair has emerged as a treatment option.

Read More...

Incidence of Acute MI After Aneurysmal Subarachnoid Hemorrhage Has Negative Effect on Hospital Outcomes

Christian D. Cerecedo-Lopez, MD, MS, and Rose Du, MD, PhD, at Brigham and Women’s Hospital, and colleagues estimate the U.S. incidence of acute myocardial infarction after aneurysmal subarachnoid hemorrhage is more than 12 times higher than previously reported.

Read More...

Embracing Clinical Innovation to Treat Cardiac Arrhythmias

William Henry Sauer, MD, section chief for Brigham’s Cardiac Arrhythmia Service, discusses how the hospital’s expert cardiologists are correcting heart rhythm disorders using a variety of electrophysiology-based treatments to relieve patients’ suffering, improve their quality of life and save lives.

Read More...