Commentary: Equitable Abortion Care for Patients With Non-English Language Preference

In this commentary, Brigham and Women’s Hospital physicians draw on their knowledge of drivers of language-related inequities to suggest best clinical practices for patients with language barriers who need abortion care. They propose ways to advance abortion equity at the clinician, health system, and societal levels.

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Brigham OB/GYN Ranks #1 in the Nation for Third Consecutive Year

Department Chair Nawal Nour, MD, MPH, MBA, reflects on U.S. News & World Report 2024-25 ranking Brigham and Women’s Hospital #1 in the nation for Obstetrics and Gynecology. She celebrates how the Department’s commitment to collaboration and transparency helps provide high quality, equitable OB/GYN care to patients.

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IVF Need Not Be Withheld From Patients With Obesity

An increasing percentage of patients seeking in vitro fertilization (IVF) are obese, and many experience disappointing outcomes. Brigham researchers recently examined the impact of increasing BMI on IVF, obstetric, and perinatal outcomes, and they report largely similar outcomes across BMIs of 30 to 60.

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Noninvasive Prenatal Test Detects Fetal Antigens

Researchers have validated a next generation sequencing (NGS)-based noninvasive prenatal test that uses quantitative counting template technology to detect RhD, C, c, E, K (Kell), and Fya (Dufy) fetal antigengenotypes from maternal blood samples in the ethnically-diverse U.S. population.

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Review: Mental Health Over the Menopause Transition

Hadine Joffe, MD, of Brigham and Women’s Hospital, and colleagues recently undertook a rigorous scientific review of whether the menopause is associated with anxiety, schizophrenic psychosis, suicidality and other mental health disorders, as has been claimed.

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New Center Aims to Close Gap in Care for Postpartum Women

Obstetrician Louise Wilkins-Haug, MD, PhD, and endocrinologist Ellen Seely, MD, are leaders at the Brigham’s Center for Connected Postpartum Care. The pair discusses the need for this center, its multidisciplinary approach to care, and its early successes in managing hypertensive patients postpartum.

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Study Focuses on Molecular Changes Associated With Different Kinds of Endometriosis Pain

Brigham gynecologist and clinical oncologist Naoko Sasamoto, MD, PhD, MPH, is focused on developing novel therapeutics that target the underlying causes of endometriosis, a disease that affects up to 10% of women of reproductive age and causes pelvic pain that can severely impact a patient’s quality of life.

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Long-term Symptom Severity, Quality of Life Comparable Across Uterine-sparing Procedures for Fibroids

Brigham researchers report long-term outcomes of COMPARE-UF, a study of women who underwent procedural treatment of uterine fibroids. They say symptom severity and quality of life were comparable with surgical and nonsurgical uterine-sparing procedures, but only hysterectomy patients showed sustained relief at year 3.

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Very-Low- and Ultra-Low-Dose Lupron Are Reasonable for Potential Poor Responders to Ovarian Stimulation

Long dosing of gonadotrophin-releasing hormone (GnRH) agonist is often used for individuals experiencing poor response to ovarian stimulation for in vitro fertilization. Brigham researchers report very-low-dose and ultra-low-dose Lupron downregulation led to similar outcomes of other protocols for poor responders.

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Validated Score Predicts Which Women Are at Risk of Midlife Declines in Physical Health and Function

Researchers at Brigham and Women’s Hospital used information from two large U.S. cohorts to derive and validate a risk score that predicts clinically meaningful midlife declines in physical health and function among women. Importantly, the score is based on variables that are easy to obtain in clinical practice.

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