In a two-part article in the Journal of Neurosurgery, surgeons at Brigham and Women’s Hospital discuss the epidemiology, clinical and radiologic features and surgical management of this group of pathologies. This summary covers part 1, dural and extradural CavVMs.

Physicians at Brigham and Women’s Hospital have encountered two newborn infants with a novel syndrome they believe arises from errors in notochord formation. They report its clinical and radiographic characteristics, describe their treatment approach and theorize about the embryogenesis of the malformation.

Serum biomarkers are becoming increasingly investigated for risk profiling in MS. Researchers at Brigham and Women’s Hospital have found that changes in two of them after treatment is stopped can signal impending disease activity.

Clinicians and clinician-investigators in the Division of Movement Disorders in the Department of Neurology at Brigham and Women’s Hospital are taking various approaches to provide specialty care for patients facing a broad range of diseases that affect movement, including Parkinson’s disease.

Researchers at Brigham and Women’s Hospital developed the Multiple Sclerosis Disease Activity (MSDA) Test, a multiprotein, serum-based biomarker assay for MS diagnosis, and have reported clinical validation of the assay.

Researchers at Brigham and Women’s Hospital believe an implanted intracranial stimulation system could increase both the strength and duration of tumor treating fields (TTF) delivery.