Category: Rheumatology

Specialty: Rheumatology

Megakaryocytes Contribute to Systemic Inflammation in Arthritis

Immunfluorescence image of megakaryocytes (green) in bone marrow, surrounded by neutrophils (ref) and other hematopoietic cells. Nuclei are labeled in blue and white outlines blood vessels.

How does a healthy joint become inflamed? This question has engaged laboratories worldwide for decades, yet surprises continue. A particularly unexpected development emerged recently from the laboratory of Brigham and Women’s Hospital (BWH) rheumatologist Peter Nigrovic, MD, (www.nigroviclab.org) which implicated a lineage that until now has been of interest primarily to hematologists: the megakaryocyte. Read More

Brigham Rheumatologists Engage in Development of New Classification System for Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a heterogeneous systemic autoimmune disease with a host of manifestations and a range of severity. Two major rheumatology associations have developed and validated SLE classification criteria in the past: the American College of Rheumatology (ACR) in 1982 with an update in 1997, and the Systemic Lupus International Collaborating Clinics (SLICC) in 2012.

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BWH Rheumatologists Receive Top Awards at ACR’s Meeting

It was another banner year for rheumatologists at Brigham and Women’s Hospital (BWH). At its annual meeting in November, the American College of Rheumatology honored three members of the Division of Rheumatology with major awards including the ACR’s highest award, the Presidential Gold Medal.   Read More

Study Compares Risk of Serious Infections Between Immunosuppressive Medications for Lupus

 

A recent BWH study found no significant difference in the risk of serious infections between two commonly prescribed immunosuppressive regimens for the treatment of SLE.

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