Brigham Establishes Department of Urology, Appoints Adam Kibel, MD, as Inaugural Chair

On October 1, 2023, Brigham and Women’s Hospital elevated its Division of Urology to a Department of Urology—the Brigham’s first new clinical and academic department in a decade. Adam S. Kibel, MD, was appointed chair of the newly established Department.

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Deconstructing Rheumatoid Arthritis Through Cell States and Pathways

New research from the Brigham is providing novel insights into rheumatoid arthritis pathology and helping to advance targeted drug development and predict treatment response. Michael Brenner, MD, and Soumya Raychaudhuri, MD, PhD, discuss the efforts of a consortium of members from academic medical centers worldwide.

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Biomarker-Based Surveillance Holds Promise for HPV-Positive Oropharynx Cancer, But Caution Is Urged

Oropharyngeal squamous cell carcinoma is growing in incidence and now seen primarily in patients with human papillomavirus (HPV). Eleni M. Rettig, MD, associate surgeon at the Brigham, recently published a review of a biomarker-based surveillance method that includes a plasma-based assay to detect circulating tumor HPV DNA post-treatment.

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New TIMI Risk Score Provides Individualized CV Risk Profile for Patients With Type 2 Diabetes

Using contemporary data sets reflecting current clinical practices, researchers at Brigham and Women’s Hospital developed the TIMI Risk Score for Atherothrombosis in Diabetes, which uses information readily available from the medical chart to predict atherothrombotic complications in patients with type 2 diabetes.

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Preoperative Alzheimer’s Disease and Related Dementias Influence Outcomes of Colorectal Surgery

Joel S. Weissman, PhD, of Brigham and Women’s Hospital, Clancy J. Clark, MD, of Wake Forest Baptist Health, and colleagues say patients with ADRD required longer hospital stays, were more likely to be readmitted, and were more likely to have postoperative complications than patients with normal cognitive function.

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Docetaxel Found to Be Significantly Associated With Reduced Prostate Cancer Mortality in Patients With Otherwise Poor Prognosis

Docetaxel

A meta-analysis of five clinical trials found that adding docetaxel to standard-of-care treatment in men with high-grade, nonmetastatic prostate cancer and low PSA levels was associated with a significant reduction in death from prostate cancer. The Brigham’s Anthony Victor D’Amico, MD, PhD, senior author of the new paper, elaborates.

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How Do Male Anxiety and Depression Affect IVF Outcomes, and Can Antidepressants Help?

A study conducted by six Brigham specialists explored the impact of men’s mental health on fertility treatment and found no difference in IVF outcomes among men with or without anxiety, regardless of antidepressant use. First author Zachary Walker, MD, discusses the paper’s key findings and clinical implications.

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Serum-based Assay Validated for Care of Patients With MS

Researchers at Brigham and Women’s Hospital developed the Multiple Sclerosis Disease Activity (MSDA) Test, a multiprotein, serum-based biomarker assay for MS diagnosis, and have reported clinical validation of the assay.

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Brigham Heart & Vascular Faculty at AHA Scientific Sessions 2023

Audience Full of People in Dark Conference Hall Watching Keynote Presentation

On November 11—13, 2023, experts from the Brigham’s Heart and Vascular Center will join thousands of colleagues in raising awareness and improving cardiovascular health at this year’s American Heart Association (AHA) Scientific Sessions.

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Most Patients Return to Work, Have Good Outcomes After ORIF for Displaced Capitellar Shear Fracture

In a retrospective study with very long-term follow-up, researchers at Brigham and Women’s Hospital found a high rate of return to work after open reduction and internal fixation (ORIF) of displaced capitellar shear fractures.

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