Latest Clinical & Research News
Immune-checkpoint blockade (ICB) therapy has been a life-changing advance for a subset of people with cancer, but additional research is needed to learn how to make these treatments more broadly effective and longer lasting. A team led by scientists at Brigham and Women’s Hospital has published a paper revealing new details about the tumor characteristics that facilitate a strong clinical response to these drugs. Read More
The 2023 ASTRO Annual Meeting – the leading meeting in radiation oncology is holding its annual conference October 1-4. Several leaders from Brigham and Women’s Hospital/Dana-Farber Brigham Cancer Center will present their latest research and clinical advancements in their particular areas of expertise in radiation oncology. Read More
Cale Jacobs, PhD, of the Department of Orthopaedic Surgery at Brigham and Women’s Hospital, and colleagues have measured the utilization of treatment for depression and anxiety after arthroscopic rotator cuff repair.
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In 1923, Dr. Elliot C. Cutler conducted the world’s first successful mitral valvuloplasty at the Brigham (then Peter Bent Brigham Hospital). On October 20, 2023, the Brigham will mark this important milestone with an all-day CME event looking at past, present, and future approaches to managing mitral valve disease.
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Axial spondyloarthritis (axSpA) is a common extraintestinal manifestation of inflammatory bowel disease (IBD). Anti-TNF agents are often used to treat concomitant axSpA and IBD. Brigham researchers have presented evidence that TNF inhibitors are less effective for axSpA than for IBD within one year.
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Brigham and Women’s Hospital researchers found moderate eGFR decline when transitioning from a renin–angiotensin system inhibitor (RASi) to SV was not consistently associated with adverse outcomes. In addition, long-term benefits of SV were retained in patients with HF across a broad range of initial eGFR declines.
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Racial/ethnic minority groups in the U.S. have higher mortality rates after surgical procedures than white individuals. Brigham and Women’s Hospital researchers have developed an analytic model of four interconnected sets of macro-level factors that influence access to high-quality, evidence-based surgical care.
Read More...Brigham scientists developed a method to simultaneously detect more than 2,000 CD1 lipid molecules that are displayed to T cells in the human immune system. This resulted in the first integrated CD1 lipidomic map, guiding the investigation of lipid T cell antigens and cleft blockers in any cellular system or disease.
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Andrew J. Schoenfeld, MD, MSc, of the Department of Orthopaedic Surgery at the Brigham, and colleagues have now validated the Stopping Opioids after Surgery (SOS) score for use after a diverse array of orthopedic procedures across subspecialties.
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A recent study co-led by Guo-Ping Shi, ScD, and Zhaojie Meng, PhD, of the Division of Cardiovascular Medicine at Brigham and Women’s Hospital, is the first to identify a receptor for eosinophil cationic protein and define its pathogenic role in atherosclerosis.
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