Latest Clinical & Research News
In this video recorded by Healio at the American Academy of Orthopaedic Surgeons Annual Meeting, Richard Iorio, MD, FAAOS, spoke about the state of physical therapy after total joint replacement.
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Brigham and Women’s Hospital researchers, and colleagues investigated the effect of combining pharmacotherapy with transoral outlet reduction. They demonstrate the combination is superior to either therapy alone and provides similar efficacy to surgical revision for weight gain after Roux-en-Y gastric bypass.
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Using two large prospective cohorts, Brigham and Women’s Hospital researchers have demonstrated that adherence to healthy practices both before and after a diabetes diagnosis is significantly associated with lower risk of microvascular complications.
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Closed-loop systems allow for concurrent sampling and modulation of extended thalamic networks. Researchers at Brigham and Women’s Hospital have become the first to capture continuous recordings of seizure activity from multiple thalamic nuclei using a closed-loop neurostimulation system.
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Metabolite levels reflect an individual’s diet, environment, and gut microbiome, and researchers at Brigham and Women’s Hospital recently became the first to find associations between plasma metabolomic profiles and persistent tinnitus.
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Multidisciplinary cancer care is crucial for uncommon and complex diseases like sarcomas, and very few cancer centers can provide the level of expert care that Dana-Farber Brigham Cancer Center can. That is because Dana-Farber Brigham has invested heavily in its clinical and research infrastructure, building a team of specialized physician-scientists and other sarcoma-focused clinicians who work closely together to provide outstanding care and drive life-changing research advances. Read More
Research suggests a significant proportion of patients experience sleep disturbances before rotator cuff repair, and the symptoms improve significantly after surgical repair. Brigham researchers have provided evidence that the resolution or persistence of sleep disturbance affects patient-reported functional outcomes.
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Measuring serum testosterone (T) levels in women aids in the diagnosis of disorders of androgen excess. Brigham and Women’s Hospital researchers examined changes in T and dihydrotestosterone levels, reporting higher levels of total and free T and emphasizing the need for menstrual phase–specific reference ranges.
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Brigham and Women’s Hospital researchers report an integrated analysis of 18 randomized, controlled trials of semaglutide (17,639 patients), concluding its safety and tolerability are now well characterized—and similar for the subcutaneous and oral formulations.
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Brigham and Women’s Hospital researchers developed a method for studying the topography of pleural epithelial structure, enabled by en face harvest and machine learning. They used its geometry to map regional differences in mechanical stress, providing key insight into normal lung function and parenchymal lung disease.
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