Latest Clinical & Research News
At the 2023 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS), Healio recorded a video of Nishant Suneja, MD, director of complex orthopaedic trauma and deformity correction at Brigham and Women’s Hospital, discussing his latest research.
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Hyperkalemia is one of the most common adverse reactions to renin–angiotensin–aldosterone system inhibitor (RAASi) therapy. In a recent study, Brigham and Women’s Hospital researchers found that patients who develop hyperkalemia while receiving RAASi therapy have a higher risk of poor outcomes.
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Mass General Brigham researchers have conducted the first study to evaluate pregnancy rates in intrauterine insemination according to both total motile count (TMC) and stimulation regimen. They report encouraging data for many patients with insemination TMC <10 million.
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Johanna Seitz-Holland, MD, instructor in the Department of Psychiatry at Brigham and Women’s Hospital, and colleagues report that the senescence-associated secretory phenotype (SASP) index of 22 proteins suggests people with late-life depression are vulnerable to accelerated physical and cognitive decline.
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Testosterone is a leading candidate for preventing and treating age-related loss of muscle mass, strength, power, and physical function. In this review, Brigham and Women’s Hospital researchers critically appraise several suppositions about using testosterone in older adults with functional limitations.
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In a new study, a Brigham team determined how nasal foralumab modulates inflammation and describes a potential novel avenue for treating not just COVID-19 but also autoimmune diseases.
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Various demyelinating diseases, including optic neuritis, transverse myelitis, acute disseminated encephalomyelitis (ADEM), and cerebral cortical encephalitis, are now recognized as a spectrum of diseases associated with high titers of autoantibodies that target myelin oligodendrocyte glycoprotein (MOG).
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Brigham and Women’s Hospital and Boston Children’s Hospital have performed the first-ever in-utero cerebrovascular surgery in the U.S. They successfully treated an aggressive vascular malformation in an infant’s brain before birth, preventing potentially fatal symptoms after delivery.
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Researchers conducted the first intraoperative imaging study for lumbar fusion, addressing the potential for selection bias and confounding by indication. They report that intraoperative CT did not significantly influence longer-term clinical outcomes after single-level instrumented procedures.
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There are no published guidelines that address oocyte retrieval techniques for assisted reproduction. Brigham and Women’s Hospital researchers surveyed physicians about their own techniques, and although no clear top-performing technique was evident, the team suggests some principles to follow.
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