Latest Clinical & Research News
Controlling a newly discovered pathway between the “anti-hunger” molecule N-lactoyl phenylalanine (Lac-Phe) and the widely prescribed diabetes drug metformin could lead to viable strategies to reduce body mass and improve health in millions of people. Lydia Lynch, PhD, and Marie McDonnell, MD, discuss their study.
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A multidisciplinary team of Mass General Brigham and Harvard Medical School investigators are drawing attention to systemic barriers to fertility preservation among sexually and gender diverse populations.
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A Brigham and Women’s Hospital study suggests endoscopic sleeve gastroplasty (ESG) is cost-saving compared with semaglutide for class II obesity due to greater effectiveness and lower costs of ESG and increased dropout rates over time with semaglutide.
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Researchers at Brigham and Women’s Hospital are using neurons derived from induced pluripotent stem cells (iNs) as a highly controlled, reproducible model system for understanding cellular pathways that mediate neuropathogenesis directly downstream of genetic risk factors.
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Researchers at Brigham and Women’s Hospital have become the first to examine the sociodemographic characteristics of patients who don’t meet the total joint arthroplasty (TJA) clinical guidelines and their rates of postoperative complications.
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Natalie Artzi, PhD, a principal investigator in the Brigham and Women’s Hospital Department of Medicine, has changed our basic understanding of biomaterials under different environmental and pathological states. Her lab is dedicated to designing smart biomaterial platforms and medical devices to improve human health.
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Using a very large U.S. prospective cohort from the Million Veteran Program, Brigham and Women’s Hospital researchers report that a higher intake of red meat, either processed or unprocessed, was associated with a higher risk of cardiovascular disease.
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Namrata Patil, MD, MPH, Anupama Singh, MD, and team compared thoracic epidural analgesia with injection of liposomal bupivacaine (LB) under direct witness in patients undergoing minimally invasive lung resection. LB intercostal block reduced opioid use 48 hours postoperatively and had fewer postoperative complications.
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Department of Orthopaedic Surgery researchers at Brigham and Women’s Hospital and colleagues recently completed a retrospective study of patients who underwent total knee arthroplasty (TKA) at age 40 or younger. They report that 15-year revision-free implant survival was comparable to rates in studies of older adults.
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Brigham and Women’s Hospital researchers and colleagues hypothesized that central adiposity, not elevated BMI alone, may have a role in fecal incontinence (FI). They report that waist circumference-to-height ratio (WtHR) is a stronger predictor of FI than BMI.
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