Latest Clinical & Research News
Matthew H. Lindsey, MD, Andrew J. Schoenfeld, MD, MSc, of the Department of Orthopaedic Surgery at Brigham and Women’s Hospital, and colleagues have published putative evidence that the C-reactive protein to albumin ratio can help predict adverse events after spinal epidural abscess treatment.
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Vikram Khurana, MD, PhD, and colleagues have discovered an additional function of α-Synuclein—it modulates the stability of mRNA, thereby regulating gene expression. They explain the implications for understanding normal cellular physiology and developing therapies for Parkinson’s disease and related disorders.
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Brigham physiatrist Danielle L. Sarno, MD, is committed to reducing chronic pain among patient populations by increasing access to interdisciplinary pain care and linking patients to pain management resources. She and Jennifer Kurz, MD, established a program to help people find long-term solutions for chronic pain.
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Kirk R. Daffner, MD, and colleagues found five weeks of cognitively stimulating activity by healthy older adults increased brain-derived neurotrophic factor (BDNF) levels and cognitive performance. They report evidence that the improvement in cognition with training was mediated by increases in BDNF.
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Hospital costs associated with anterior cervical decompression and fusion (ACDF) are highly heterogeneous. Andrew K. Simpson, MD, MBA, MHS, the Department of Orthopaedic Surgery at Brigham and Women’s Hospital, and colleagues conducted the first rigorous analysis of the relative drivers of ACDF costs.
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On November 5—7, 2022, experts from the Brigham’s Heart and Vascular Center will join thousands of colleagues in raising awareness and improving cardiovascular health at this year’s American Heart Association (AHA) Scientific Sessions.
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In the first study of its kind, Brigham and Women’s Hospital researchers showed that individuals with rheumatic conditions residing in neighborhoods with high social or heat vulnerability have greater odds of recurrent hospitalization than those with lower vulnerability.
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Thomas R. McCarty, MD, MPH, Christopher C. Thompson, MD, and colleagues recently constructed a computer model to evaluate the cost-effectiveness of various strategies for treating gastroesophageal reflux disease (GERD) that is refractory to standard-dose proton pump inhibitor (PPI) therapy.
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Christopher C. Thompson, MD, director of endoscopy and co-director of the Center for Weight Management and Wellness at Brigham and Women’s Hospital, and colleagues are studying a novel bariatric and metabolic procedure to weaken the antral pump, a major physiologic component of gastric emptying.
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Brigham researchers confirmed that non-heart failure (HF) hospitalizations are burdensome for patients who have HF with preserved ejection fraction (HFpEF), who tend to have more noncardiac comorbidities than patients who have HF with reduced ejection fraction.
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