Utility of a Neurosurgical “Boot Camp” for Medical Students

Diverse group of men and women in white lab coats learning, arm raised to ask question

Garth Rees Cosgrove, MD, Michael A. Mooney, MD, of the Department of Neurosurgery at Brigham and Women’s Hospital, and colleagues recently organized a pilot in-person cadaveric workshop for medical students. It included hands-on teaching of craniotomy-related skills by neurosurgery faculty and residents.

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Review: Environmental Sustainability in the Orthopaedic Operating Room

Close up of surgeon putting on blue gloves in operating room

Operating rooms (ORs), including orthopedic ORs, contribute substantially to greenhouse gas emissions because of the high amount of energy used and waste generated. A recent review explains steps orthopedic surgeons can take to improve environmental sustainability.

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Study Finds Drug Benefits Heart Failure Patients With Normal Ejection Fraction

Cardiologist showing patient an anatomical model of human heart, sitting at desk

A team led by Brigham investigators has reported findings from a study looking at whether heart failure patients with mildly reduced or preserved ejection fraction could benefit from treatment with the sodium-glucose cotransporter 2 inhibitor dapagliflozin. First author Scott David Solomon, MD, shares his perspective.

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Predictors of Healthcare Spending Identified in Patients With Gout Using Urate-lowering Therapy

Female patient in office signing paperwork across from doctor

Researchers at Brigham and Women’s Hospital identified three distinct groups of gout patients according to their patterns of total spending on health care. The team provides information on identifying patients with gout who could benefit from interventions to reduce long-term spending.

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The Value of Geriatric Expertise in Care of Older Emergency General Surgery Patients

Young female nurse with mask looks down at older patient in wheelchair in front of bright window

In 2020, the Brigham launched a geriatric surgical service to improve outcomes and quality of care for older emergency general surgery patients. A paper details the care of patients at the service and the important role of geriatricians in serving this patient population, co-author Frances Y. Hu explains.

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Brigham Researchers Create COVID-19 Genome Catalog of the Human Microbiome

3D rendering of the human gut microbiome, with different gut species

Researchers at Brigham and Women’s Hospital analyzed whole-metagenome shotgun (WMS) sequencing data by reconstructing microbial population genomes directly from microbiome samples of COVID-19 patients and controls. They report the creation of the first high-quality COVID-19–related genome catalog of the gut microbiome.

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Treatment Within Five Days Generally Appropriate for Dural Arteriovenous Fistula–related Hemorrhage

MRI of the brain, Intracerebral hemorrhages, cerebral vascular disease (stroke)

Rose Du, MD, PhD, and colleagues completed the largest-ever analysis of patients with cranial dural arteriovenous fistulas (dAVF) hemorrhage. They report that treatment within five days was associated with a low rate of an early rebleed and appears to be an appropriate timeframe.

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Female Orthopedic Surgeons Blaze New Trails at the Brigham

Diverse surgical team performing operation

Women constitute about 6% of practicing orthopedic surgeons, but at the Brigham, the ratio is 6 out of 34, or 17.6%. Meet three of the Brigham’s female orthopedic surgical faculty—Antonia Chen, MD, Elizabeth Martin, MD, ScM, and Elizabeth G. Matzkin, MD—all of whom are innovators in research and clinical care.

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Brain Lesions Associated With Addiction Remission Map to a Common Circuit

3D rendering of human head with brain activity colored fibers

It’s possible to link lesions in different brain locations to a common neuroanatomical substrate using the human connectome. Using this approach, Brigham researchers have identified specific testable targets for therapeutic neuromodulation of nicotine addiction.

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Understanding Calcium Pyrophosphate Deposition Disease: Q&A With Sara Tedeschi, MD, MPH

Eldery woman in wheelchair feeling arthritis discomfort in right knee

Calcium pyrophosphate deposition (CPPD) disease affects 8-10 million adults in the U.S., yet knowledge of CPPD lags far behind that of gout and other types of inflammatory arthritis. The Brigham’s Sara Tedeschi, MD, MPH, and the research team are working to understand the disease better and improve patient care.

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