Latest Clinical & Research News
Advances in telemedicine are enabling the Brigham to bring high-quality neurosurgical care to patients nationally and internationally. Timothy R. Smith, MD, PhD, MPH, of the Department of Neurosurgery, discusses how these efforts reflect the broader movement to meet patients’ right to healthcare globally.
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Researchers at Brigham and Women’s Hospital recently completed the first large multicenter study of the incidence of ST-segment–elevation myocardial infarction (STEMI) as a complication of COVID-19. STEMI was rare in 0.35% of patients but was associated with poor in-hospital outcomes and high mortality.
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A potential cardiovascular benefit of vupanorsen would best be reflected by its effects on non–high-density lipoprotein cholesterol (non–HDL-C) and apolipoprotein B (ApoB). Brigham researchers studied vupanorsen at higher doses and observed significant reductions in non–HDL-C at all doses studied.
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In a post hoc analysis of the PARAGON-HF trial, Scott D. Solomon, MD, of the Division of Cardiovascular Medicine at Brigham and Women’s Hospital, and colleagues evaluated how atrial fibrillation and atrial flutter affected the results.
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Surgeons in the Department of Orthopaedic Surgery at Brigham and Women’s Hospital recently reviewed the evidence for and against pronator quadratus (PQ) muscle repair.
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A groundbreaking intranasal vaccine for Alzheimer’s disease (AD) developed at Brigham shows tremendous promise in its first phase of human trials. Study leader Howard L. Weiner, MD, discusses the trial’s progress to date, planned future phases, and how the vaccine could shape the future of AD care.
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The REDUCE-IT trial found patients at risk had reduced important ischemic events with icosapent ethyl. Prakriti Gaba, MD, and Deepak L. Bhatt, MD, MPH, of Brigham and Women’s Hospital, and colleagues, conducted a post hoc analysis limited to patients in the trial who had a history of myocardial infarction (MI).
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Mass General Brigham Neurology Residency leaders recently revised its parental leave policy to better embody equity, fairness, transparency, and wellness values. They discuss the impact of the updated policy and offer suggestions for other programs that wish to implement a parental leave policy with similar goals.
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Once the final chest drain is removed after cardiothoracic surgery, it is common practice to obtain a chest X-ray to evaluate for air or fluid that may have accumulated in the process of drain removal. However, the results of a retrospective study at Brigham and Women’s Hospital suggest routine imaging isn’t necessary.
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Patients with ulcerative colitis who require total proctocolectomy with ileal pouch–anal anastomosis can develop a chronic pouch disorder. Because some patients treated with ustekinumab lost response, Brigham researchers explored the effects of intensifying the dosage and found it safe and effective.
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