Latest Clinical & Research News
Leaders from the Brigham’s Department of Pediatric Newborn Medicine presented their latest research to thousands of attendees at the 2022 Pediatric Academic Societies’ meeting. The department had a strong presence at this event, which took place April 21 – 25, 2022, in Denver, CO.
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The Division of Cardiac Surgery earned a distinguished three-star rating from The Society of Thoracic Surgeons (STS) for patient care and outcomes in isolated coronary artery bypass grafting procedures. George Tolis, MD, section chief of Coronary Surgery and General Cardiac Surgery, explains the rating and its meaning.
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Through brain imaging and laboratory research, Brigham investigators are examining how lithium affects the brain at the individual neuron and brain-circuit levels. Psychiatrist Amit Anand, MD, explains how it may increase the growth of certain areas of the brain and influence the organ functionally and structurally.
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The Brigham has launched an academic center for the healthcare needs of transgender and gender-diverse people. Devin O’Brien-Coon, MD, MS, clinical director and surgical co-director, discusses the impetus for founding the Center for Transgender Health and what he expects its multidisciplinary team will accomplish.
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The Brigham’s Venkat M. Ramakrishnan, MD, PhD, and colleagues are the first to systematically assess residual gas (RPP) with CT after laparoscopy. They presenta tableto help clinicians determine whether RPP at a particular time point after robotic-assisted laparoscopic prostatectomy (RALP) is in the expected range.
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Vanita Aroda, MD, associate physician in the Division of Endocrinology, Diabetes and Hypertension, has served as a clinical researcher and clinical trialist for countless studies focused on preventing and treating type 2 diabetes. She discusses her involvement in the SELECT, PIONEER 1, REVITALIZE 1, and other trials.
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Gergo Merkely, MD, and colleagues wondered whether extensive trauma and greater traction on the patella tendon might induce an inflammatory response that increases the risk of postoperative stiffness. They report evidence that, indeed, TTO-HD is an independent risk factor for postoperative arthrofibrosis.
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A post hoc analysis of the ATHENA trial has determined that dronedarone has benefits in patients whose atrial fibrillation or atrial flutter is complicated by heart failure with preserved ejection fraction or heart failure with mildly reduced ejection fraction.
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Brigham researchers found that miR-10b seems to regulate mRNA splicing, suggesting an exciting new approach to research not just in glioma but in cancer more generally.
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Researchers at the Ann Romney Center for Neurologic Diseases at the Brigham, and colleagues have affirmed miR-92a as a powerful, clinically relevant target in multiple sclerosis and give preliminary information about the effects of inhibiting miR-92a in central nervous system autoimmune disease.
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