Myocardial Blood Flow Reserve Is an Early Marker of Myocardial Decompensation in Patients with Aortic Stenosis

Echocardiography image doppler of aortic stenosis

Marcelo F. DiCarli, MD, of the Cardiovascular Imaging Program at the Brigham, and Wunan Zhou, MD, MPH, at the NIH, and colleagues report that impaired myocardial blood flow reserve is an early marker of adverse myocardial characteristics and can identify patients who might benefit from aortic valve replacement.

Read More...

Incidental CT Findings Influence Subjective, Objective Chronic Rhinosinusitis Scores

Axial plain / sagittal cut of CT scan showing inflammation of both sides maxillary sinuses

Researchers at Brigham and Women’s Hospital sought to answer whether the association between SNOT-22 and CT results could be improved by rating partial opacification more precisely. Instead, they found the relationship between the two assessment methods is affected by incidental causes of opacification.

Read More...

Gastric Sensors May Improve Patient Monitoring in Critical Care Settings

Nurses prepare a nasogastric tube

Giovanni Traverso, MB, BChir, PhD, of Brigham and Women’s Hospital and MIT, and colleagues found in models that gastric fluid (GF), accessible through an ordinary nasogastric tube, contains many of the biomarkers associated with diseases treated in critical care settings.

Read More...

What Are the Best Treatment Options for Epilepsy That Doesn’t Respond to Medications?

3-D segmented coronal MRI demonstrating bilateral deep brain stimulation.

Physicians at the Brigham are developing various treatments to improve seizure control for patients with epilepsy. As Garth Rees Cosgrove, MD, director of epilepsy and functional neurosurgery, explains, these therapies require a great deal of diagnostic and surgical expertise along with the latest cutting-edge tools.

Read More...

Comprehensive Geriatric Assessment Successfully Adapted to Telehealth

Patient uses a tablet for telehealth visit with doctor

The COVID-19 pandemic had prompted a 130-fold increase in telehealth visits by U.S. Medicare recipients. The Division of Aging at the Brigham was part of that surge, adapting the comprehensive geriatric assessment (CGA) to be suitable for telephone and video visits.

Read More...

Morbidity and Mortality from Mitral Valve Surgery After TEER: First CUTTING-EDGE Data

Team of cardiologists perform transcatheter closure treatment

Tsuyoshi Kaneko, MD, of the Heart & Vascular Center at Brigham, served as the first author of the initial analysis of CUTTING-EDGE data. Two key findings are that 93% of patients required MV replacement and one-year cumulative mortality for the entire cohort was 24%.

Read More...

Case Series: MRI-guided Focused Ultrasound Thalamotomy

David J. Segar, MD, and G. Rees Cosgrove, MD, at Brigham and Women’s Hospital, and colleagues have reported the largest single-surgeon series of focused ultrasound thalamotomy to date. They demonstrate tremor relief and adverse event rates consistent with previous reports and present new information about predictors…

Read More...

Active Lifestyle May Reduce Incidence of Obstructive Sleep Apnea

Yue Liu, MD, a research fellow at the Brigham, Tianyi Huang, ScD, an associate epidemiologist, and colleagues have linked physical inactivity and sedentary behavior with obstructive sleep apnea incidence, suggesting an active lifestyle may have a role in prevention.

Read More...

Expanding the Role for Metastasectomy in Advanced-Stage Melanoma

Historically, stage 4 melanoma was considered incurable. In these cases, metastasectomy was performed for only as a palliative measure. But with recent advancements in systemic therapy, metastasectomy has emerged as an effective tool for extending the period of disease control and enhancing overall treatment response. Dana-Farber Brigham Cancer Center is at the forefront of this transformation.

Read More

Urology Subspecialists Are Still Predominantly White, Male

Building a racially/ethnically representative urology workforce is becoming even more important. Elodi J. Dielubanza, MD, associate surgeon in the Division of Urology at Brigham and Women’s Hospital, and colleagues recently conducted the first study that describes demographic trends in urologic subspecialties.

Read More...