Latest Clinical & Research News
Elena Losina, MD, PhD, of the Department of Orthopaedic Surgery, and colleagues estimate the total lifetime cost of opioid use among patients with symptomatic knee osteoarthritis is $14 billion. 47% of that cost is unrelated to pain management or other clinical care.
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In September 2021, the Heart Failure Society of America published a scientific statement that discusses clinical care for patients with HF during the COVID-19 pandemic. Ankeet S. Bhatt, MD, MBA, of the Division of Cardiovascular Medicine at the Brigham, was a co-chair of the writing committee and first author.
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George E. Haleblian, MD, urologic surgeon in the Division of Urology at the Brigham, and colleagues applied TDABC to acute urolithiasis. They report wide variation in costs between care pathways, suggesting opportunities to trim inefficient or wasteful services.
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Stefan G. Tullius, MD, PhD, of the Brigham, and colleagues, pinpointed taurodeoxycholic acid (TDCA), a bile acid, and L-valine, an essential amino acid, as agents that replicate many benefits of SG. In eLife they say their results may lead to improved pharmacologic treatment of obesity in humans.
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Jeffrey N. Katz, MD, MS, Elena Losina, PhD, and colleagues found that structural changes in the knee detected after arthroscopic partial meniscectomy are not clinically meaningful during the first years of follow-up.
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Giovanni Traverso, MD, PhD, MBBCH, a gastroenterologist in the Division of Gastroenterology, Hepatology and Endoscopy at the Brigham and MIT, and colleagues have created L-SOMA, a version of the SOMA capsule, which injects liquid formulations of pharmaceuticals into the gastric submucosa.
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Sonia Friedman, MD, the Center for Crohn’s and Colitis, Bente Mertz Nørgård, DMSc, MD, PhD, and colleagues conducted the first population-based study to evaluate postpartum surgical complications in women with IBD. They report strikingly higher rates after Cesarian section than after vaginal delivery.
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Brigham researchers are seeking to limit the severe effects of respiratory viruses by using new methods to reduce the viral load and excessive lung inflammation that are common with these lung infections. Pulmonologist Bruce D. Levy, MD, is a corresponding author of a recently published article on this research.
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Sameer Hirji, MD, MPH, and Tsuyoshi Kaneko, MD, of the Division of Cardiac Surgery at the Brigham, and colleagues summarize the revised recommendations about caring for patients with secondary mitral regurgitation now that transcatheter edge-to-edge mitral repair has emerged as a treatment option.
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Christian D. Cerecedo-Lopez, MD, MS, and Rose Du, MD, PhD, at Brigham and Women’s Hospital, and colleagues estimate the U.S. incidence of acute myocardial infarction after aneurysmal subarachnoid hemorrhage is more than 12 times higher than previously reported.
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