Factors That Warrant Screening for Thoracolumbar Spine Fracture After TBI

To determine when additional imaging may be advisable, Hasan A. Zaidi, MD, and Blake M. Hauser of the Computational Neurosurgical Outcomes Center in the Department of Neurosurgery at Brigham and Women’s Hospital, and colleagues identified common risk factors for thoracic and lumbar spinal fractures in TBI.

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Avoiding Long-Term Consequences of Gestational Diabetes

Ellen W. Seely, MD, director of clinical research in the Endocrinology, Diabetes and Hypertension Division, discusses the Brigham’s proactive approach to mitigating the impact of gestational diabetes on mothers, fetuses and newborn babies.

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Helping Women Navigate Changes in Their Pelvic Health

Elodi Dielubanza, MD, associate surgeon in the Brigham’s Division of Urology, is seeking to normalize female urinary tract and pelvic floor disorders. She helps patients with these disorders to restore their normal daily function through surgery, medications, physical therapy and behavior modification.

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Targeting Common Causal Circuits With Brain Stimulation to Treat Depression

Can targeting certain brain circuits with therapeutic stimulation modulate neuropsychiatric symptoms? A recent study involving multiple Brigham and Women’s Hospital investigators including Michael D. Fox, MD, PhD, and Shan H. Siddiqi, MD, MBBS, answers that crucial question in the affirmative.

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Embracing Clinical Innovation to Treat Cardiac Arrhythmias

William Henry Sauer, MD, section chief for Brigham’s Cardiac Arrhythmia Service, discusses how the hospital’s expert cardiologists are correcting heart rhythm disorders using a variety of electrophysiology-based treatments to relieve patients’ suffering, improve their quality of life and save lives.

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Can Degenerative Disc Disease Be Treated Without Invasive Surgery?

Brigham and Women’s Hospital investigators led by James D. Kang, MD, chair of the Department of Orthopaedic Surgery, and Shuichi Mizuno, PhD, are exploring new technology and a groundbreaking approach to slow down and even prevent intervertebral disc degeneration without resorting to surgery.

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SGLT2 Inhibitors Have Similar Benefits to GLP-1 Receptor Agonists for Myocardial Infarction or Stroke but Greater Benefits for Hospitalization for Heart Failure in Patients with Type 2 Diabetes

Exenatide diabetes drug molecule

Practice guidelines recommend considering sodium–glucose cotransporter-2 (SGLT2) inhibitors or glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for patients who have both diabetes and atherosclerotic cardiovascular disease (CVD). The choice between the drug classes is left to the physician, except that SGLT2 inhibitors are advised for patients with a history of heart failure.

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Childhood Exposure to Parental Smoking Increases Risk of Rheumatoid Arthritis in Adulthood

A hand and wrist x-ray showing severe arthritis of the wrist or carpus and Boutonniere deformity of the thumb.

Active cigarette smoking is the best-established modifiable risk factor for the development of rheumatoid arthritis (RA), but whether passive smoking can be linked to RA is unclear.

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Perspectives: Immune-mediated Inflammatory Disease Therapeutics

woman using a wheelchair in a park;

Over the past two decades, the treatment of immune-mediated inflammatory diseases (IMID) has moved from broad-spectrum immune modulators to agents that have exquisite specificity. Substantial toxicity is no longer the norm, and remission or low states of disease activity are typical outcomes.

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Brigham and Women’s Rheumatology at ACR Convergence 2021

Ellen M. Gravallese, MD

Faculty of the Division of Rheumatology, Inflammation and Immunity at Brigham and Women’s Hospital played a prominent role at the American College of Rheumatology’s annual Convergence conference, which ran virtually from November 3 through November 10, 2021.

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