Advancing Care for Traumatic Spine Injuries

Spine X-Ray
This 27-year-old patient experienced a severe L2-L3 fracture/dislocation after hitting a tree in a high-speed downhill skiing accident. They were treated with L2-3 lateral interbody fusion and returned to full functional activity with no pain.

Treating patients with traumatic spinal cord injuries has significant challenges, in large part because of the potentially severe and life-altering effects these injuries can have. Despite recent progress in finding the best way to treat spinal cord damage, many patients are left with profound disabilities. Additional research, both in the lab and the clinic, is vital.

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Are Previous Notions of Atherosclerosis Outdated?

Peter Libby, MD with research lab colleagues
Peter Libby, MD, (left) with research laboratory colleagues

Once a problem primarily in developed, Western nations, atherosclerosis is on the rise in developing countries and has become a major cause of morbidity and mortality worldwide. As the burden of atherosclerosis has shifted geographically and socioeconomically, the way in which the disease is approached and treated has shifted as well. Peter Libby, MD, a cardiovascular medicine specialist at Brigham and Women’s Hospital, has helped drive the latter of these changes.

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Trials Address New Options for Tricuspid Valve Defects

Tricuspid Valve

The tricuspid valve is often referred to as the “forgotten valve.” That’s because when it begins to malfunction, it usually doesn’t result in the same severity of symptoms as when there are problems with the aortic and mitral valves. Additionally, when it does stop working properly, fewer interventions are available for treatment.

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Brigham and Women’s Takes Novel Approach to Correcting Neurocardiogenic Syncope

woman with hand on her forehead

Fainting is a fairly common reaction to painful or emotional stimuli. It is especially common in young children, but most people eventually grow out of it or are able to manage the occasional occurrence. For a small group of people, however, neurocardiogenic syncope becomes debilitating, with fainting spells happening every couple of weeks, often without any provoking factors.

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Brigham Ahead of the Curve on Implementing New Asthma Care Guidelines to Transform Patients’ Lives

Woman sitting on bed with hand to chest as if having trouble breathing

When new clinical care guidelines are issued, it often can take years before they are widely inculcated among practicing physicians. However, in the case of new asthma care guidelines issued in 2020, Brigham and Women’s Hospital has been implementing the recommended new treatment approaches for several years.

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NIH-Funded Efforts Center on How MicroRNAs Regulate Women’s Health

Pregnant woman and partner with hand on bellyClinical studies for new drugs and vaccines, including the recent trials that led to the approval of COVID-19 vaccines, generally exclude women who are pregnant or lactating. For that reason, little is known about how hormonal changes affect drug pharmacokinetics and pharmacodynamics.

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New Procedure Extends Coverage in Patients With Non-Valvular Afib

Masked doctors in operating room

As part of its continuing mission to innovate safer, more effective treatments, the Cardiac Arrhythmia Service at Brigham and Women’s Hospital has introduced a new version of a minimally invasive procedure for people with non-valvular atrial fibrillation (Afib). The procedure, which currently uses the WATCHMAN™ FLX device, extends the option of left atrial appendage (LAA) closure to patients who may not have qualified for it before.

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Addressing Questions Related to Brain Health and Health Care Disparities After Hemorrhagic Stroke

brain scan

A team that includes investigators from Brigham and Women’s Hospital, Massachusetts General Hospital and Boston University School of Medicine is one of three multidisciplinary groups that recently received funding from the Henrietta B. and Frederick H. Bugher Foundation to develop breakthroughs related to hemorrhagic stroke. The over $11 million gift, which the American Heart Association is overseeing, aims to improve prevention, treatment and health outcomes for patients with intracerebral hemorrhage.

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Building Bridges Between Clinicians and Biomedical Engineers to Improve Clinical Care in Africa

illustration of globe and stethoscope

Many countries in Africa are facing a severe shortage of clinicians in many specialties, including neurosurgery. Although efforts are underway to train more young clinicians and expand access to neurosurgical care across the continent, another gap must also be addressed: the lack of collaboration between neurosurgeons and technical experts.

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Innovating Lung Transplant Protocols During the COVID-19 Surge

illustration of lung interiorHospitals across the country pushed the pause button on elective surgeries and non-emergency procedures during the early days of the COVID-19 pandemic. However, patients requiring lifesaving organ transplants couldn’t wait. To meet these patients’ urgent needs, the transplant team at the Brigham and Women’s Hospital Lung Center sprang into action, quickly creating new protocols to help the sickest of the sick.

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