Focusing on Outcomes of Treatment for Shoulder Instability

shoulder x-rayShoulder instability is a relatively common concern in athletes, especially among those who play contact sports such as football, basketball and rugby. This condition has a number of treatment options, including physical therapy and various surgical procedures, but much remains unclear about how to determine the best course for each patient.

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Some Obesity-Linked Diseases May Be Related to Cholesterol

close up of cellsObesity is linked to an increased risk of many diseases, but much remains unknown about the molecular mechanisms underlying this connection. In a new study from Brigham and Women’s Hospital and Harvard Medical School, investigators have found an unexpected role for cholesterol and its effects on the immune system in driving some of these obesity-linked diseases — in particular, with conditions characterized by autoimmunity.

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Using Nanoparticles to Target Renal Cell Carcinoma

nanoparticlesTargeted therapy has had much less success in treating renal cell carcinoma than in treating many other kinds of cancer. Physician-scientists at Brigham and Women’s Hospital are working on several innovative approaches to address this shortfall.

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Lessons Learned From Adapting the CGA for Telehealth

People using tablet at homeThe COVID-19 pandemic has sparked a rapid shift to telemedicine across health care. Among the many challenges this new reality has created for geriatricians is how to adapt the comprehensive geriatric assessment (CGA) to a virtual delivery format.

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Emphasizing Prevention in Alzheimer’s Disease Trials

alzheimer's researchFor most chronic diseases, improvements in care over the past few decades have resulted from early interventions that prevent disease progression. Brigham and Women’s Hospital investigators, along with collaborators at other institutions around the world, are applying a similar approach to the early detection and prevention of Alzheimer’s disease (AD).

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Brigham Offers Comprehensive Approach to Afib Management

Ablation imaging
Detailed, accurate renderings such as this one help guide operators during ablation, without use of fluoroscopy, enabling a safe, effective, and efficient ablation procedure.

The Heart & Vascular Center at Brigham and Women’s Hospital has a well-established reputation for innovation in atrial fibrillation (Afib) treatment. Twenty years ago, the Brigham pioneered cryoablation therapy, which currently comprises about 20 percent of Afib ablations conducted worldwide.

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Neoadjuvant Immunotherapy for Head & Neck Cancer Patients

Neoadjuvant Immunotherapy
Image of tumor sample from a patient who demonstrated pathologic response to neoadjuvant pembrolizumab (10X magnification, courtesy of Dr. Rebecca Chernock)

Researchers at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC) are advancing innovative approaches to decrease tumor recurrence rates in patients with HPV-negative squamous cell carcinoma of the head and neck (SCCHN).

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The Lung Center Provides Specialized Treatment for TBM

Chest CT scan
Chest CT: 62-year-old woman with tracheomalacia and emphysema.

An often-misdiagnosed lung condition is receiving special attention from a multidisciplinary team of specialists at The Lung Center at Brigham and Women’s Hospital.

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Studying Pandemic’s Effect on Mental Health in Young Adults

Young adults in masks at schoolThe COVID-19 pandemic has been challenging for almost everyone, and different populations have been hit in different ways. For people aged 18–30 years, it has had an outsized effect on mental health, especially in terms of depression, anxiety and post-traumatic stress disorder (PTSD).

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Study Finds RA not Associated With Increased Type 2 DM Risk

Person doing finger prick for diabetesDoes rheumatoid arthritis (RA) raise the risk of developing type 2 diabetes mellitus (DM)? Previous epidemiologic studies have drawn varying conclusions. Now, a large population-based cohort study bolsters the case that RA in fact is not associated with a heightened risk.

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